The BEST Neow Relics in Slay the Spire 2

PC Game

Year2026

Watch Now

0

Which Neow relics actually help you WIN runs in Slay the Spire 2? Today we’re ranking every Neow relic based on consistency, early-game strength, scaling potential, and how reliable they are for climbing Ascensions. Some relics completely solve your early game, while others look amazing but quietly make runs much harder. This isn’t just a basic tier list. We’re talking about which Neow relics actually lead to stronger runs over time, including some controversial placements and underrated starts. If you’ve ever wondered: Which Neow relic is the best? Which relics are bait? Which starts are the most consistent? What makes a strong Act 1 start? Which Neow relics help climb Ascensions? …this video should help a lot. Slay the Spire 2 Tier List Gameplay & Strategy Guide. And check out my twitch link below. I stream Monday, Tuesday, Thursday, and Friday night at 9pm EST on twitch. https://www.twitch.tv/nerdyhickey https://www.twitter.com/rhickey28 https://www.tiktok.com/@nerdyhickey #slaythespire2 #slaythespire #roguelike #deckbuilder